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Tara Sigdel, Ph.D.

Tara Sigdel, Ph.D.

  • Associate Professor of Surgery
  • Division of Transplant Surgery

Contact Information

513 Parnassus Ave, Med Sci
San Francisco CA 94143
[email protected]
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B.Sc. (Biology and Chemistry) Tribhuvan University, Kathmandu, Nepal

M.Sc. (Chemistry) Tribhuvan University, Kathmandu, Nepal, Advisor: Prof. Vishwanath Pd. Agrawal, PhD

Ph.D. (Biochemistry), Miami University, Oxford, OH, Advisor: Prof. Michael Crowder, PhD

  • N/A
  • Postdoctoral Training, Dept of Pediatrics-nephrology, Stanford University, Stanford, CA
  • Advisor: Prof. Minnie Sarwal MD. PhD.
  • Bioinformatics
  • Biomarker DIscovery
  • High Throughput Data
  • Immunology
  • Kidney Transplantation
  • Liver Cancer
  • Organ Transplantation
  • Proteomics

Tara Sigdel, Ph.D. obtained his Ph.D. in biochemistry from Miami University (OH) followed by postdoctoral training in biomarker discovery, immunology, and organ transplantation at Stanford University under Professor Minnie Sarwal. Dr Sigdel joined the UCSF Department of Surgery in 2014 where he uses proteomics, immune response profiling, and gene expression analysis to discover sensitive and effective biomarkers that help in developing clinical tools for early diagnosis and improved patient monitoring. In collaboration with researchers at UCSF and other institutes, Dr. Sigdel is actively involved in identification of non-invasive biomarkers genes, peptides, proteins, and antibodies that monitor disease status after organ transplantation.

  Award  
  Confired By    
  Date    
  • Pediatric Research Fund – CHRP Award
  • Stanford University, Stanford, CA
  • 2009 - 2010
  • Pediatric Research Fund – CHRP Award
  • Stanford University, Stanford, CA
  • 2008 - 2009
  • Deans Postdoctoral Fellowship
  • Stanford University, Stanford, CA
  • 2007 - 2008
  • Doctoral-Undergraduate Opportunities in Scholarship (DUOS) award for two consecutive years (2003 and
  • Miami University, Oxford, OH
  • 2003 - 2005
  • William Hale Charch Graduate Fellowship
  • Miami University, Oxford, OH
  • 2002 - 2003
  • Dr. Sigdel's research is driven by two major factors. First, there is an unprecedented pressure to deliver new and improved diagnostic and treatment options to patients. Second, due to improved understanding of biological intricacies with ever improving molecular assays have placed us in a much better position to look for disease specific biomarkers that once validated can be used in the clinics in order to provide timely and accurate assessment of health status of patients.

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 99
    Data provided by UCSF Profiles, powered by CTSI
    1. Sigdel TK, Sur S, Boada P, McDermott SM, Arlehamn CSL, Murray KO, Bockenstedt LK, Kerwin M, Reed EF, Harris E, Stuart K, Peters B, Sesma A, Montgomery RR, Sarwal MM. Proteome Analysis for Inflammation Related to Acute and Convalescent Infection. Inflammation. 2023 Oct 13. View in PubMed
    2. Lamarthée B, Callemeyn J, Van Herck Y, Antoranz A, Anglicheau D, Boada P, Becker JU, Debyser T, De Smet F, De Vusser K, Eloudzeri M, Franken A, Gwinner W, Koshy P, Kuypers D, Lambrechts D, Marquet P, Mathias V, Rabant M, Sarwal MM, Senev A, Sigdel TK, Sprangers B, Thaunat O, Tinel C, Van Brussel T, Van Craenenbroeck A, Van Loon E, Vaulet T, Bosisio F, Naesens M. Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection. Nat Commun. 2023 07 19; 14(1):4359. View in PubMed
    3. Sigdel TK, Boada P, Kerwin M, Rashmi P, Gjertson D, Rossetti M, Sur S, Munar D, Cimino J, Ahn R, Pickering H, Sen S, Parmar R, Fatou B, Steen H, Schaenman J, Bunnapradist S, Reed EF, Sarwal MM, CMV Systems Immunobiology Group. Plasma proteome perturbation for CMV DNAemia in kidney transplantation. PLoS One. 2023; 18(5):e0285870. View in PubMed
    4. Rashmi P, Sigdel TK, Rychkov D, Damm I, Da Silva AA, Vincenti F, Lourenco AL, Craik CS, Reiser J, Sarwal MM. Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors. Ann Transl Med. 2023 Jun 30; 11(9):315. View in PubMed
    5. Boada P, Fatou B, Belperron AA, Sigdel TK, Smolen KK, Wurie Z, Levy O, Ronca SE, Murray KO, Liberto JM, Rashmi P, Kerwin M, Montgomery RR, Bockenstedt LK, Steen H, Sarwal MM. Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection. Front Immunol. 2022; 13:1012824. View in PubMed
    6. View All Publications

     

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